File:Liu Neurosci Res 2025.pdfLiu, J., Goto, A. & Hayashi, Y. (in press) Time-window of offline long-term potentiation in anterior cingulate cortex during memory consolidation and recall. Neurosci. Res.
Pandey,V., Hosokawa, T. Hayashi, Y. & Urakubo, H. (in press) Multiphasic protein condensation
governed by shape and valency. Cell Reports
2024
Kaizuka, T., Hirouchi, T., Saneyoshi, T., Shirafuji, T., Collins, M.O., Grant, S.G.N., Hayashi, Y., & Takumi, T. (2024).
FAM81A is a postsynaptic protein that regulates the condensation of postsynaptic proteins via liquid-liquid phase separation. PLoS biology, 22(3), e3002006.
[PubMed:38452102]
[PMC]
[WorldCat]
[DOI]
2023
Ripoli, C., Dagliyan, O., Renna, P., Pastore, F., Paciello, F., Sollazzo, R., Rinaudo, M., Battistoni, M., Martini, S., Tramutola, A., Sattin, A., Barone, E., Saneyoshi, T., Fellin, T., Hayashi, Y., & Grassi, C. (2023).
Engineering memory with an extrinsically disordered kinase. Science advances, 9(46), eadh1110.
[PubMed:37967196]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2022
Özden, C., Sloutsky, R., Mitsugi, T., Santos, N., Agnello, E., Gaubitz, C., Foster, J., Lapinskas, E., Esposito, E.A., Saneyoshi, T., Kelch, B.A., Garman, S.C., Hayashi, Y., & Stratton, M.M. (2022).
CaMKII binds both substrates and activators at the active site. Cell reports, 40(2), 111064.
[PubMed:35830796]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2021
Goto, A., Bota, A., Miya, K., Wang, J., Tsukamoto, S., Jiang, X., Hirai, D., Murayama, M., Matsuda, T., McHugh, T.J., Nagai, T., & Hayashi, Y. (2021).
Stepwise synaptic plasticity events drive the early phase of memory consolidation. Science (New York, N.Y.), 374(6569), 857-863.
[PubMed:34762472]
[WorldCat]
[DOI]
[Google Scholar]
Cid, E., Marquez-Galera, A., Valero, M., Gal, B., Medeiros, D.C., Navarron, C.M., Ballesteros-Esteban, L., Reig-Viader, R., Morales, A.V., Fernandez-Lamo, I., Gomez-Dominguez, D., Sato, M., Hayashi, Y., Bayés, À., Barco, A., Lopez-Atalaya, J.P., & de la Prida, L.M. (2021).
Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis. Cell reports, 35(10), 109229.
[PubMed:34107264]
[WorldCat]
[DOI]
[Google Scholar]
Takamura, R., Mizuta, K., Sekine, Y., Islam, T., Saito, T., Sato, M., Ohkura, M., Nakai, J., Ohshima, T., Saido, T.C., & Hayashi, Y. (2021).
Modality-Specific Impairment of Hippocampal CA1 Neurons of Alzheimer's Disease Model Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(24), 5315-5329.
[PubMed:33980545]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Hosokawa, T., Liu, P.W., Cai, Q., Ferreira, J.S., Levet, F., Butler, C., Sibarita, J.B., Choquet, D., Groc, L., Hosy, E., Zhang, M., & Hayashi, Y. (2021).
CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation. Nature neuroscience, 24(6), 777-785.
[PubMed:33927400]
[WorldCat]
[DOI]
[Google Scholar]
Kastian, R.F., Minegishi, T., Baba, K., Saneyoshi, T., Katsuno-Kambe, H., Saranpal, S., Hayashi, Y., & Inagaki, N. (2021).
Shootin1a-mediated actin-adhesion coupling generates force to trigger structural plasticity of dendritic spines. Cell reports, 35(7), 109130.
[PubMed:34010643]
[WorldCat]
[DOI]
[Google Scholar]
Eriksen, M.S., Nikolaienko, O., Hallin, E.I., Grødem, S., Bustad, H.J., Flydal, M.I., Merski, I., Hosokawa, T., Lascu, D., Akerkar, S., Cuéllar, J., Chambers, J.J., O'Connell, R., Muruganandam, G., Loris, R., Touma, C., Kanhema, T., Hayashi, Y., Stratton, M.M., Valpuesta, J.M., Kursula, P., Martinez, A., & Bramham, C.R. (2021).
Arc self-association and formation of virus-like capsids are mediated by an N-terminal helical coil motif. The FEBS journal, 288(9), 2930-2955.
[PubMed:33175445]
[WorldCat]
[DOI]
[Google Scholar]
Sato, M., Mizuta, K., Islam, T., Kawano, M., Sekine, Y., Takekawa, T., Gomez-Dominguez, D., Schmidt, A., Wolf, F., Kim, K., Yamakawa, H., Ohkura, M., Lee, M.G., Fukai, T., Nakai, J., & Hayashi, Y. (2020).
Distinct Mechanisms of Over-Representation of Landmarks and Rewards in the Hippocampus. Cell reports, 32(1), 107864.
[PubMed:32640229]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Luchetti, A., Bota, A., Weitemier, A., Mizuta, K., Sato, M., Islam, T., McHugh, T.J., Tashiro, A., & Hayashi, Y. (2020).
Two Functionally Distinct Serotonergic Projections into Hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(25), 4936-4944.
[PubMed:32414785]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Cai, Q., Hosokawa, T., Zeng, M., Hayashi, Y., & Zhang, M. (2020).
Shank3 Binds to and Stabilizes the Active Form of Rap1 and HRas GTPases via Its NTD-ANK Tandem with Distinct Mechanisms. Structure (London, England : 1993), 28(3), 290-300.e4.
[PubMed:31879129]
[WorldCat]
[DOI]
[Google Scholar]
2019
Kojima, H., Rosendale, M., Sugiyama, Y., Hayashi, M., Horiguchi, Y., Yoshihara, T., Ikegaya, Y., Saneyoshi, T., & Hayashi, Y. (2019).
The role of CaMKII-Tiam1 complex on learning and memory. Neurobiology of learning and memory, 166, 107070.
[PubMed:31445077]
[WorldCat]
[DOI]
[Google Scholar]
Saneyoshi, T., Matsuno, H., Suzuki, A., Murakoshi, H., Hedrick, N.G., Agnello, E., O'Connell, R., Stratton, M.M., Yasuda, R., & Hayashi, Y. (2019).
Reciprocal Activation within a Kinase-Effector Complex Underlying Persistence of Structural LTP. Neuron, 102(6), 1199-1210.e6.
[PubMed:31078368]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Ghandour, K., Ohkawa, N., Fung, C.C.A., Asai, H., Saitoh, Y., Takekawa, T., Okubo-Suzuki, R., Soya, S., Nishizono, H., Matsuo, M., Osanai, M., Sato, M., Ohkura, M., Nakai, J., Hayashi, Y., Sakurai, T., Kitamura, T., Fukai, T., & Inokuchi, K. (2019).
Orchestrated ensemble activities constitute a hippocampal memory engram. Nature communications, 10(1), 2637.
[PubMed:31201332]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Kobayashi, T., Islam, T., Sato, M., Ohkura, M., Nakai, J., Hayashi, Y., & Okamoto, H. (2019).
Wide and Deep Imaging of Neuronal Activities by a Wearable NeuroImager Reveals Premotor Activity in the Whole Motor Cortex. Scientific reports, 9(1), 8366.
[PubMed:31182818]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Kim, K., Suzuki, A., Kojima, H., Kawamura, M., Miya, K., Abe, M., Yamada, I., Furuse, T., Wakana, S., Sakimura, K., & Hayashi, Y. (2019).
Autophosphorylation of F-actin binding domain of CaMKIIβ is required for fear learning. Neurobiology of learning and memory, 157, 86-95.
[PubMed:30528771]
[WorldCat]
[DOI]
Hallin, E.I., Eriksen, M.S., Baryshnikov, S., Nikolaienko, O., Grødem, S., Hosokawa, T., Hayashi, Y., Bramham, C.R., & Kursula, P. (2018).
Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities. Journal of neurochemistry, 147(3), 323-343.
[PubMed:30028513]
[WorldCat]
[DOI]
Kashino, Y., Obara, Y., Okamoto, Y., Saneyoshi, T., Hayashi, Y., & Ishii, K. (2018).
ERK5 Phosphorylates Kv4.2 and Inhibits Inactivation of the A-Type Current in PC12 Cells. International journal of molecular sciences, 19(7).
[PubMed:29996472]
[PMC]
[WorldCat]
[DOI]
Sato, M., Kawano, M., Mizuta, K., Islam, T., Lee, M.G., & Hayashi, Y. (2017).
Hippocampus-Dependent Goal Localization by Head-Fixed Mice in Virtual Reality. eNeuro, 4(3).
[PubMed:28484738]
[PMC]
[WorldCat]
[DOI]
Bosch, M., Castro, J., Sur, M., & Hayashi, Y. (2017).
Photomarking Relocalization Technique for Correlated Two-Photon and Electron Microcopy Imaging of Single Stimulated Synapses. Methods in molecular biology (Clifton, N.J.), 1538, 185-214.
[PubMed:27943192]
[WorldCat]
[DOI]
Sato, M., Kawano, M., Yanagawa, Y., & Hayashi, Y. (2016).
In vivo two-photon imaging of striatal neuronal circuits in mice. Neurobiology of learning and memory, 135, 146-151.
[PubMed:27400866]
[WorldCat]
[DOI]
[Google Scholar]
2015
Kim, K., Lakhanpal, G., Lu, H.E., Khan, M., Suzuki, A., Hayashi, M.K., Narayanan, R., Luyben, T.T., Matsuda, T., Nagai, T., Blanpied, T.A., Hayashi, Y., & Okamoto, K. (2015).
A Temporary Gating of Actin Remodeling during Synaptic Plasticity Consists of the Interplay between the Kinase and Structural Functions of CaMKII. Neuron, 87(4), 813-26.
[PubMed:26291163]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Hosokawa, T., Mitsushima, D., Kaneko, R., & Hayashi, Y. (2015).
Stoichiometry and phosphoisotypes of hippocampal AMPA-type glutamate receptor phosphorylation. Neuron, 85(1), 60-67.
[PubMed:25533481]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Sato, M., Kawano, M., Ohkura, M., Gengyo-Ando, K., Nakai, J., & Hayashi, Y. (2015).
Generation and Imaging of Transgenic Mice that Express G-CaMP7 under a Tetracycline Response Element. PloS one, 10(5), e0125354.
[PubMed:25946002]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Sakaguchi, M., Kim, K., Yu, L.M., Hashikawa, Y., Sekine, Y., Okumura, Y., Kawano, M., Hayashi, M., Kumar, D., Boyden, E.S., McHugh, T.J., & Hayashi, Y. (2015).
Inhibiting the Activity of CA1 Hippocampal Neurons Prevents the Recall of Contextual Fear Memory in Inducible ArchT Transgenic Mice. PloS one, 10(6), e0130163.
[PubMed:26075894]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Matsuno, H., Ohi, K., Hashimoto, R., Yamamori, H., Yasuda, Y., Fujimoto, M., Yano-Umeda, S., Saneyoshi, T., Takeda, M., & Hayashi, Y. (2015).
A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia. PloS one, 10(3), e0116319.
[PubMed:25768306]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Manita, S., Suzuki, T., Homma, C., Matsumoto, T., Odagawa, M., Yamada, K., Ota, K., Matsubara, C., Inutsuka, A., Sato, M., Ohkura, M., Yamanaka, A., Yanagawa, Y., Nakai, J., Hayashi, Y., Larkum, M.E., & Murayama, M. (2015).
A Top-Down Cortical Circuit for Accurate Sensory Perception. Neuron, 86(5), 1304-16.
[PubMed:26004915]
[WorldCat]
[DOI]
[Google Scholar]
2014
Bosch, M., Castro, J., Saneyoshi, T., Matsuno, H., Sur, M., & Hayashi, Y. (2014).
Structural and molecular remodeling of dendritic spine substructures during long-term potentiation. Neuron, 82(2), 444-59.
[PubMed:24742465]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Martinez-Lozada, Z., Waggener, C.T., Kim, K., Zou, S., Knapp, P.E., Hayashi, Y., Ortega, A., & Fuss, B. (2014).
Activation of sodium-dependent glutamate transporters regulates the morphological aspects of oligodendrocyte maturation via signaling through calcium/calmodulin-dependent kinase IIβ's actin-binding/-stabilizing domain. Glia, 62(9), 1543-1558.
[PubMed:24866099]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2013
Ueda, Y., & Hayashi, Y. (2013).
PIP₃ regulates spinule formation in dendritic spines during structural long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(27), 11040-7.
[PubMed:23825409]
[PMC]
[WorldCat]
[DOI]
Wang, D.O., Matsuno, H., Ikeda, S., Nakamura, A., Yanagisawa, H., Hayashi, Y., & Okamoto, A. (2012).
A quick and simple FISH protocol with hybridization-sensitive fluorescent linear oligodeoxynucleotide probes. RNA (New York, N.Y.), 18(1), 166-75.
[PubMed:22101241]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2011
Mower, A.F., Kwok, S., Yu, H., Majewska, A.K., Okamoto, K., Hayashi, Y., & Sur, M. (2011).
Experience-dependent regulation of CaMKII activity within single visual cortex synapses in vivo. Proceedings of the National Academy of Sciences of the United States of America, 108(52), 21241-6.
[PubMed:22160721]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2009
Hayashi, M.K., Tang, C., Verpelli, C., Narayanan, R., Stearns, M.H., Xu, R.M., Li, H., Sala, C., & Hayashi, Y. (2009).
The postsynaptic density proteins Homer and Shank form a polymeric network structure. Cell, 137(1), 159-71.
[PubMed:19345194]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Kishi, K., van Vugt, M.A., Okamoto, K., Hayashi, Y., & Yaffe, M.B. (2009).
Functional dynamics of Polo-like kinase 1 at the centrosome. Molecular and cellular biology, 29(11), 3134-50.
[PubMed:19307309]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2008
Niemann, S., Landers, J.E., Churchill, M.J., Hosler, B., Sapp, P., Speed, W.C., Lahn, B.T., Kidd, K.K., Brown, R.H., & Hayashi, Y. (2008).
Motoneuron-specific NR3B gene: no association with ALS and evidence for a common null allele. Neurology, 70(9), 666-76.
[PubMed:17687115]
[WorldCat]
[DOI]
Kwok, S., Lee, C., Sánchez, S.A., Hazlett, T.L., Gratton, E., & Hayashi, Y. (2008).
Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity. Biochemical and biophysical research communications, 369(2), 519-25.
[PubMed:18302935]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2007
Futai, K., Kim, M.J., Hashikawa, T., Scheiffele, P., Sheng, M., & Hayashi, Y. (2007).
Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin. Nature neuroscience, 10(2), 186-95.
[PubMed:17237775]
[PMC]
[WorldCat]
[DOI]
Okamoto, K., Narayanan, R., Lee, S.H., Murata, K., & Hayashi, Y. (2007).
The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure. Proceedings of the National Academy of Sciences of the United States of America, 104(15), 6418-23.
[PubMed:17404223]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Niemann, S., Kanki, H., Fukui, Y., Takao, K., Fukaya, M., Hynynen, M.N., Churchill, M.J., Shefner, J.M., Bronson, R.T., Brown, R.H., Watanabe, M., Miyakawa, T., Itohara, S., & Hayashi, Y. (2007).
Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes. The European journal of neuroscience, 26(6), 1407-20.
[PubMed:17880385]
[WorldCat]
[DOI]
[Google Scholar]
Kim, M.J., Futai, K., Jo, J., Hayashi, Y., Cho, K., & Sheng, M. (2007).
Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95. Neuron, 56(3), 488-502.
[PubMed:17988632]
[WorldCat]
[DOI]
[Google Scholar]
2006
Okamoto, K., & Hayashi, Y. (2006).
Visualization of F-actin and G-actin equilibrium using fluorescence resonance energy transfer (FRET) in cultured cells and neurons in slices. Nature protocols, 1(2), 911-9.
[PubMed:17406324]
[WorldCat]
[DOI]
[Google Scholar]
Hayashi, M.K., Ames, H.M., & Hayashi, Y. (2006).
Tetrameric hub structure of postsynaptic scaffolding protein homer. The Journal of neuroscience : the official journal of the Society for Neuroscience, 26(33), 8492-501.
[PubMed:16914674]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2005
Takao, K., Okamoto, K., Nakagawa, T., Neve, R.L., Nagai, T., Miyawaki, A., Hashikawa, T., Kobayashi, S., & Hayashi, Y. (2005).
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 25(12), 3107-12.
[PubMed:15788767]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Howarth, M., Takao, K., Hayashi, Y., & Ting, A.Y. (2005).
Targeting quantum dots to surface proteins in living cells with biotin ligase. Proceedings of the National Academy of Sciences of the United States of America, 102(21), 7583-8.
[PubMed:15897449]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Fukaya, M., Hayashi, Y., & Watanabe, M. (2005).
NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons. The European journal of neuroscience, 21(5), 1432-6.
[PubMed:15813953]
[WorldCat]
[DOI]
[Google Scholar]
Nolan, E.M., Jaworski, J., Okamoto, K., Hayashi, Y., Sheng, M., & Lippard, S.J. (2005).
QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). Journal of the American Chemical Society, 127(48), 16812-23.
[PubMed:16316228]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2004
Okamoto, K., Nagai, T., Miyawaki, A., & Hayashi, Y. (2004).
Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nature neuroscience, 7(10), 1104-12.
[PubMed:15361876]
[WorldCat]
[DOI]
[Google Scholar]
Nakagawa, T., Futai, K., Lashuel, H.A., Lo, I., Okamoto, K., Walz, T., Hayashi, Y., & Sheng, M. (2004).
Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions. Neuron, 44(3), 453-67.
[PubMed:15504326]
[WorldCat]
[DOI]
[Google Scholar]
Li, Z., Okamoto, K., Hayashi, Y., & Sheng, M. (2004).
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell, 119(6), 873-87.
[PubMed:15607982]
[WorldCat]
[DOI]
[Google Scholar]
Chang, C.J., Nolan, E.M., Jaworski, J., Okamoto, K., Hayashi, Y., Sheng, M., & Lippard, S.J. (2004).
ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy. Inorganic chemistry, 43(21), 6774-9.
[PubMed:15476377]
[WorldCat]
[DOI]
[Google Scholar]
Semino, C.E., Kasahara, J., Hayashi, Y., & Zhang, S. (2004).
Entrapment of migrating hippocampal neural cells in three-dimensional peptide nanofiber scaffold. Tissue engineering, 10(3-4), 643-55.
[PubMed:15165480]
[WorldCat]
[DOI]
[Google Scholar]
2003
Sala, C., Futai, K., Yamamoto, K., Worley, P.F., Hayashi, Y., & Sheng, M. (2003).
Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homer1a. The Journal of neuroscience : the official journal of the Society for Neuroscience, 23(15), 6327-37.
[PubMed:12867517]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Kawamura M, Namba H, Otsu. Y, Hayashi Y, Takei N, Nawa H Characterization of novel bicistronic sindbis virus vectors, SinEGdsp and SinIRES-EG, in cultured neurons. Recent Res. Devel. Neurochem.: 2003 6():105-120.
Jourdi, H., Iwakura, Y., Narisawa-Saito, M., Ibaraki, K., Xiong, H., Watanabe, M., Hayashi, Y., Takei, N., & Nawa, H. (2003).
Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons. Developmental biology, 263(2), 216-30.
[PubMed:14597197]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2001
Shi, S., Hayashi, Y., Esteban, J.A., & Malinow, R. (2001).
Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons. Cell, 105(3), 331-43.
[PubMed:11348590]
[WorldCat]
[DOI]
[Google Scholar]
Nishi, M., Hinds, H., Lu, H.P., Kawata, M., & Hayashi, Y. (2001).
Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner. The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(23), RC185.
[PubMed:11717388]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2000
Zhu, J.J., Esteban, J.A., Hayashi, Y., & Malinow, R. (2000).
Postnatal synaptic potentiation: delivery of GluR4-containing AMPA receptors by spontaneous activity. Nature neuroscience, 3(11), 1098-106.
[PubMed:11036266]
[WorldCat]
[DOI]
[Google Scholar]
Hayashi, Y., Shi, S.H., Esteban, J.A., Piccini, A., Poncer, J.C., & Malinow, R. (2000).
Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science (New York, N.Y.), 287(5461), 2262-7.
[PubMed:10731148]
[WorldCat]
[DOI]
[Google Scholar]
Carlezon, W.A., Haile, C.N., Coppersmith, R., Hayashi, Y., Malinow, R., Neve, R.L., & Nestler, E.J. (2000).
Distinct sites of opiate reward and aversion within the midbrain identified using a herpes simplex virus vector expressing GluR1. The Journal of neuroscience : the official journal of the Society for Neuroscience, 20(5), RC62.
[PubMed:10684909]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
1999
Shi, S.H., Hayashi, Y., Petralia, R.S., Zaman, S.H., Wenthold, R.J., Svoboda, K., & Malinow, R. (1999).
Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science (New York, N.Y.), 284(5421), 1811-6.
[PubMed:10364548]
[WorldCat]
[DOI]
[Google Scholar]
Mainen, Z.F., Maletic-Savatic, M., Shi, S.H., Hayashi, Y., Malinow, R., & Svoboda, K. (1999).
Two-photon imaging in living brain slices. Methods (San Diego, Calif.), 18(2), 231-9, 181.
[PubMed:10356355]
[WorldCat]
[DOI]
[Google Scholar]
1997
Hayashi, Y., Ishida, A., Katagiri, H., Mishina, M., Fujisawa, H., Manabe, T., & Takahashi, T. (1997).
Calcium- and calmodulin-dependent phosphorylation of AMPA type glutamate receptor subunits by endogenous protein kinases in the post-synaptic density. Brain research. Molecular brain research, 46(1-2), 338-42.
[PubMed:9191113]
[WorldCat]
[DOI]
[Google Scholar]
1996
Sekiyama, N., Hayashi, Y., Nakanishi, S., Jane, D.E., Tse, H.W., Birse, E.F., & Watkins, J.C. (1996).
Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. British journal of pharmacology, 117(7), 1493-503.
[PubMed:8730745]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
1994
Okamoto, N., Hori, S., Akazawa, C., Hayashi, Y., Shigemoto, R., Mizuno, N., & Nakanishi, S. (1994).
Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction. The Journal of biological chemistry, 269(2), 1231-6.
[PubMed:8288585]
[WorldCat]
[Google Scholar]
Kaba, H., Hayashi, Y., Higuchi, T., & Nakanishi, S. (1994).
Induction of an olfactory memory by the activation of a metabotropic glutamate receptor. Science (New York, N.Y.), 265(5169), 262-4.
[PubMed:8023145]
[WorldCat]
[DOI]
[Google Scholar]
Hayashi, Y., Sekiyama, N., Nakanishi, S., Jane, D.E., Sunter, D.C., Birse, E.F., Udvarhelyi, P.M., & Watkins, J.C. (1994).
Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 14(5 Pt 2), 3370-7.
[PubMed:8182479]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
1993
Sugimoto, Y., Negishi, M., Hayashi, Y., Namba, T., Honda, A., Watabe, A., Hirata, M., Narumiya, S., & Ichikawa, A. (1993).
Two isoforms of the EP3 receptor with different carboxyl-terminal domains. Identical ligand binding properties and different coupling properties with Gi proteins. The Journal of biological chemistry, 268(4), 2712-8.
[PubMed:8381413]
[WorldCat]
[Google Scholar]
Negishi, M., Sugimoto, Y., Hayashi, Y., Namba, T., Honda, A., Watabe, A., Narumiya, S., & Ichikawa, A. (1993).
Functional interaction of prostaglandin E receptor EP3 subtype with guanine nucleotide-binding proteins, showing low-affinity ligand binding. Biochimica et biophysica acta, 1175(3), 343-50.
[PubMed:8382086]
[WorldCat]
[DOI]
[Google Scholar]
Hayashi, Y., Momiyama, A., Takahashi, T., Ohishi, H., Ogawa-Meguro, R., Shigemoto, R., Mizuno, N., & Nakanishi, S. (1993).
Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb. Nature, 366(6456), 687-90.
[PubMed:7903116]
[WorldCat]
[DOI]
[Google Scholar]
1992
Sugimoto, Y., Namba, T., Honda, A., Hayashi, Y., Negishi, M., Ichikawa, A., & Narumiya, S. (1992).
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype. The Journal of biological chemistry, 267(10), 6463-6.
[PubMed:1372606]
[WorldCat]
[Google Scholar]
Namba, T., Sugimoto, Y., Hirata, M., Hayashi, Y., Honda, A., Watabe, A., Negishi, M., Ichikawa, A., & Narumiya, S. (1992).
Mouse thromboxane A2 receptor: cDNA cloning, expression and northern blot analysis. Biochemical and biophysical research communications, 184(3), 1197-203.
[PubMed:1375456]
[WorldCat]
[DOI]
[Google Scholar]
Hayashi, Y., Tanabe, Y., Aramori, I., Masu, M., Shimamoto, K., Ohfune, Y., & Nakanishi, S. (1992).
Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells. British journal of pharmacology, 107(2), 539-43.
[PubMed:1330184]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
1991
Hirata, M., Hayashi, Y., Ushikubi, F., Yokota, Y., Kageyama, R., Nakanishi, S., & Narumiya, S. (1991).
Cloning and expression of cDNA for a human thromboxane A2 receptor. Nature, 349(6310), 617-20.
[PubMed:1825698]
[WorldCat]
[DOI]
[Google Scholar]
1990
Koshimura, K., Miwa, S., Lee, K., Hayashi, Y., Hasegawa, H., Hamahata, K., Fujiwara, M., Kimura, M., & Itokawa, Y. (1990).
Effects of choline administration on in vivo release and biosynthesis of acetylcholine in the rat striatum as studied by in vivo brain microdialysis. Journal of neurochemistry, 54(2), 533-9.
[PubMed:2299351]
[WorldCat]
[DOI]
[Google Scholar]
Hayashi, Y., Miwa, S., Lee, K., Koshimura, K., Hamahata, K., Hasegawa, H., Fujiwara, M., & Watanabe, Y. (1990).
Enhancement of in vivo tyrosine hydroxylation in the rat adrenal gland under hypoxic conditions. Journal of neurochemistry, 54(4), 1115-21.
[PubMed:1968954]
[WorldCat]
[DOI]
[Google Scholar]
1989
Lee, K., Miwa, S., Hayashi, Y., Koshimura, K., Fujiwara, M., & Orii, Y. (1989).
Effects of hypoxia on noradrenaline release and neuronal reuptake in isolated rabbit thoracic aortic strips. Naunyn-Schmiedeberg's archives of pharmacology, 339(5), 503-8.
[PubMed:2770884]
[WorldCat]
[DOI]
[Google Scholar]
1988
Hayashi, Y., Miwa, S., Lee, K., Koshimura, K., Kamel, A., Hamahata, K., & Fujiwara, M. (1988).
A nonisotopic method for determination of the in vivo activities of tyrosine hydroxylase in the rat adrenal gland. Analytical biochemistry, 168(1), 176-83.
[PubMed:2896473]
[WorldCat]
[DOI]
[Google Scholar]
Lee, K., Miwa, S., Hayashi, Y., Koshimura, K., Taniguchi, T., Orii, Y., & Fujiwara, M. (1988).
Effects of hypoxia on contractile responses of rabbit aortic strips to transmural electrical stimulation. Naunyn-Schmiedeberg's archives of pharmacology, 338(3), 275-81.
[PubMed:3194036]
[WorldCat]
[DOI]
[Google Scholar]
Reviews and Commentaries
2017
Lissek, T., Adams, M., Adelman, J., Ahissar, E., Akaaboune, M., Akil, H., al'Absi, M., Arain, F., Arango-Lasprilla, J.C., Atasoy, D., Avila, J., Badawi, A., Bading, H., Baig, A.M., Baleriola, J., Belmonte, C., Bertocchi, I., Betz, H., Blakemore, C., Blanke, O., Boehm-Sturm, P., Bonhoeffer, T., Bonifazi, P., Brose, N., Campolongo, P., Celikel, T., Chang, C.C., Chang, T.Y., Citri, A., ..., & Hasan, M.T. (2017).
Building Bridges through Science. Neuron, 96(4), 730-735.
[PubMed:29144972]
[WorldCat]
[DOI]
[Google Scholar]
2016
Kim, K., Saneyoshi, T., Hosokawa, T., Okamoto, K., & Hayashi, Y. (2016).
Interplay of enzymatic and structural functions of CaMKII in long-term potentiation. Journal of neurochemistry, 139(6), 959-972.
[PubMed:27207106]
[WorldCat]
[DOI]
[Google Scholar]
2014
Saneyoshi, T., & Hayashi, Y. (2014).
Synapse reorganization-a new partnership revealed. The EMBO journal, 33(12), 1292-4.
[PubMed:24764316]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Kim, K., & Hayashi, Y. (2014).
CaMKII: the Swiss army knife of synaptic plasticity. The Journal of physiology, 592(22), 4807-8.
[PubMed:25399030]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2013
Ueda, Y., Kwok, S., & Hayashi, Y. (2013).
Application of FRET probes in the analysis of neuronal plasticity. Frontiers in neural circuits, 7, 163.
[PubMed:24133415]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2012
Saneyoshi, T., & Hayashi, Y. (2012).
The Ca2+ and Rho GTPase signaling pathways underlying activity-dependent actin remodeling at dendritic spines. Cytoskeleton (Hoboken, N.J.), 69(8), 545-54.
[PubMed:22566410]
[WorldCat]
[DOI]
[Google Scholar]
Sakaguchi, M., & Hayashi, Y. (2012).
Catching the engram: strategies to examine the memory trace. Molecular brain, 5, 32.
[PubMed:22999350]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
Hayashi, Y., Okamoto, K., Bosch, M., & Futai, K. (2012).
Roles of neuronal activity-induced gene products in Hebbian and homeostatic synaptic plasticity, tagging, and capture. Advances in experimental medicine and biology, 970, 335-54.
[PubMed:22351063]
[WorldCat]
[DOI]
[Google Scholar]
Bosch, M., & Hayashi, Y. (2012).
Structural plasticity of dendritic spines. Current opinion in neurobiology, 22(3), 383-8.
[PubMed:21963169]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2010
Malinow, R., Hayashi, Y., Maletic-Savatic, M., Zaman, S.H., Poncer, J.C., Shi, S.H., Esteban, J.A., Osten, P., & Seidenman, K. (2010).
Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection. Cold Spring Harbor protocols, 2010(4), pdb.prot5406.
[PubMed:20360360]
[PMC]
[WorldCat]
[DOI]
[Google Scholar]
2009
Okamoto, K., Bosch, M., & Hayashi, Y. (2009).
The roles of CaMKII and F-actin in the structural plasticity of dendritic spines: a potential molecular identity of a synaptic tag? Physiology (Bethesda, Md.), 24, 357-66.
[PubMed:19996366]
[WorldCat]
[DOI]
[Google Scholar]
Poo, M.M., Sander, L., Fivaz, M., & Hayashi, Y. (2008).
Asian promise: the state and future of collaborations in neuroscience. Nature reviews. Neuroscience, 9(11), 881-4.
[PubMed:18843270]
[WorldCat]
[DOI]
[Google Scholar]
2005
Hayashi, Y., & Majewska, A.K. (2005).
Dendritic spine geometry: functional implication and regulation. Neuron, 46(4), 529-32.
[PubMed:15944122]
[WorldCat]
[DOI]
K Futai, Y Hayashi
Dynamism of postsynaptic proteins as the mechanism of synaptic plasticity
In Excitatory-Inhibitory Balance, Synapses, Circuits, Systems pp. 45-58, edited by Hensch and Fagiolini. Springer, 2003
[Google Scholar]
2000
Malinow, R., Mainen, Z.F., & Hayashi, Y. (2000).
LTP mechanisms: from silence to four-lane traffic. Current opinion in neurobiology, 10(3), 352-7.
[PubMed:10851179]
[WorldCat]
[DOI]
Malinow, R., Hayashi, Y., Maletic-Savatic, M., Zaman, S.H., Poncer, J.C., Shi, S.H., Esteban, J.A., Osten, P., & Seidenman, K. (2010).
Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection. Cold Spring Harbor protocols, 2010(4), pdb.prot5406.
[PubMed:20360360]
[PMC]
[WorldCat]
[DOI]
1996
Nakanishi, S., Nakajima, Y., Nomura, A., Masu, M., Iwakabe, H., Hayashi, Y., & Yokoi, M. (1996).
Functions and roles of glutamate receptors in synaptic transmission and plasticity. Cold Spring Harbor symposia on quantitative biology, 61, 67-75.
[PubMed:9246436]
[WorldCat]
[Google Scholar]
1994
Nakanishi, S., Masu, M., Bessho, Y., Nakajima, Y., Hayashi, Y., & Shigemoto, R. (1994).
Molecular diversity of glutamate receptors and their physiological functions. EXS, 71, 71-80.
[PubMed:8032174]
[WorldCat]
[DOI]
[Google Scholar]
1993
Narumiya, S., Hirata, N., Namba, T., Hayashi, Y., Ushikubi, F., Sugimoto, Y., Negishi, M., & Ichikawa, A. (1993).
Structure and function of prostanoid receptors. Journal of lipid mediators, 6(1-3), 155-61.
[PubMed:8395239]
[WorldCat]
